Last updated 1 week ago

Disruptability [+]

Species Disruptability Reference Submitter
P. berghei ANKA
Refractory
RMgm-963 Imported from RMgmDB
P. yoelii yoelii 17X
Possible
RMgm-4513 Imported from RMgmDB
P. yoelii yoelii 17X
Possible
RMgm-4889 Imported from RMgmDB

Mutant phenotypes [+]

Species Stage Phenotype Reference Submitter
P. yoelii yoelii 17X Asexual
No difference
RMgm-4513 Imported from RMgmDB
P. yoelii yoelii 17X Asexual
No difference
RMgm-4889 Imported from RMgmDB
P. yoelii yoelii 17X Gametocyte
No difference
RMgm-4513 Imported from RMgmDB
P. yoelii yoelii 17X Gametocyte
No difference
RMgm-4889 Imported from RMgmDB
P. yoelii yoelii 17X Ookinete
Difference from wild-type
RMgm-4889
Both isp1 and isp3 mutants showed normal development of asexual blood stages and gametocytes in vivo as well as gamete formation and zygote-to-retort differentiation in vitro. However, the mature ookinete conversion in vitro was significantly reduced in isp1 (conversion rate: 34%) but not in isp3 (57%) compared with wild type (WT, 64%)
Imported from RMgmDB

More information

PlasmoDB PCHAS_1210100
GeneDB PCHAS_1210100
Malaria Metabolic Pathways Localisation images
Pathways mapped to
Previous ID(s) PCHAS_121010
Orthologs PBANKA_1209400 , PF3D7_1011000 , PKNH_0810800 , PVP01_0811100 , PVX_094770 , PY17X_1212600
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