Disruptability [+]

Species Disruptability Reference Submitter
P. berghei ANKA
Possible
RMgm-588 Imported from RMgmDB
P. falciparum 3D7
Possible
USF piggyBac screen (Insert. mut.) USF PiggyBac Screen

Mutant phenotypes [+]

Species Stage Phenotype Reference Submitter
P. berghei ANKA Asexual
No difference
RMgm-588 Imported from RMgmDB
P. berghei ANKA Gametocyte
Difference from wild-type
RMgm-588
Normal production of male and female gametocytes. Normal rates of male gamete formation as measured by the number of exflagellating male gametocytes. Male gametes showed reduced motility and fertility, with 50% of male gametes being immotile (see also 'Additional information phenotype').
Imported from RMgmDB
P. berghei ANKA Ookinete
Difference from wild-type
RMgm-588
Normal production of male and female gametocytes. Normal rates of male gamete formation as measured by the number of exflagellating male gametocytes. Male gametes showed reduced motility and fertility, with 50% of male gametes being immotile. The fertilisation rate as measured by the in vitro formation of ookinete was 20% compared to 70-80% in wild type gametes.
Imported from RMgmDB
P. berghei ANKA Oocyst
Difference from wild-type
RMgm-588
The fertilisation rate of gametes as measured by the in vitro formation of ookinete was 20% compared to 70-80% in wild type gametes. Ookinetes formed in vivo during a mosquito feed are able to give rise to a significant number of oocysts and generate normal sporozoites that are infectious to mice.
Imported from RMgmDB
P. berghei ANKA Sporozoite
Difference from wild-type
RMgm-588
The fertilisation rate of gametes as measured by the in vitro formation of ookinete was 20% compared to 70-80% in wild type gametes. Ookinetes formed in vivo during a mosquito feed are able to give rise to a significant number of oocysts and generate normal sporozoites that are infectious to mice.
Imported from RMgmDB
P. berghei ANKA Liver
Difference from wild-type
RMgm-588
The fertilisation rate of gametes as measured by the in vitro formation of ookinete was 20% compared to 70-80% in wild type gametes. Ookinetes formed in vivo during a mosquito feed are able to give rise to a significant number of oocysts and generate normal sporozoites that are infectious to mice.
Imported from RMgmDB

More information

PlasmoDB PCHAS_0928600
GeneDB PCHAS_0928600
Malaria Metabolic Pathways Localisation images
Pathways mapped to
Previous ID(s) PC000547.01.0, PC301884.00.0, PC301885.00.0, PCAS_092860, PCHAS_092860
Orthologs PBANKA_0917400 , PF3D7_1130800 , PKNH_0928900 , PVP01_0931600 , PVX_092145 , PY17X_0919000
Google Scholar Search for all mentions of this gene