Disruptability [+]

Species Disruptability Reference Submitter
P. berghei ANKA
Refractory
PlasmoGEM (Barseq) PlasmoGEM
P. falciparum 3D7
Refractory
USF piggyBac screen (Insert. mut.) USF PiggyBac Screen

Mutant phenotypes [+]

None reported yet. Please press the '+' button above to add one.

Imaging data (from Malaria Metabolic Pathways)

FPPS/GGPPS localization. Images of live parasites (FPPS/GGPPS-HA-GFP strain) expressing GFP and immunofluorescence of the FPPS/GGPPS-HA strain visualized by fluorescence or confocal microscopy. (A) Images of live parasites FPPS/GGPPS-HA-GFP by fluorescence microscopy during the intra-erythrocytic cycle of the parasite. (B) Bottom -immunofluorescence of the FPPS/GGPPS-HA strain with antibody as indicated, visualized by confocal microscopy. Top—Images of live FPPS/GGPPS-HA-GFP parasites with markers as indicated, visualized by confocal microscopy. ET1 (early rophozoites); ET2 (early trophozoites); LT (latetrophozoites); LT (late trophozoites) S1 (schizont); S2 (schizont); R (rosettes); M (Merozoites); DAPI (nucleus marker). Original magnification for all images: 1.000×Gabriel HB, de Azevedo MF, Palmisano G, Wunderlich G, Kimura EA, Katzin AM, Alves JM. Single-target high-throughput transcription analyses reveal high levels of alternative splicing present in the FPPS/GGPPS from Plasmodium falciparum. Sci Rep. 2015. PMID:

See original on MMP

More information

PlasmoDB PCHAS_0924600
GeneDB PCHAS_0924600
Malaria Metabolic Pathways Localisation images
Pathways mapped to
Previous ID(s) PC000417.01.0, PC000556.03.0, PCAS_092460, PCHAS_092460
Orthologs PBANKA_0919800 , PF3D7_1128400 , PKNH_0926500 , PVP01_0929200 , PVX_092040 , PY17X_0921900
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