Disruptability [+]

Species Disruptability Reference Submitter
P. berghei ANKA
Possible
RMgm-909 Imported from RMgmDB
P. berghei ANKA
Possible
PlasmoGEM (Barseq) PlasmoGEM
P. falciparum 3D7
Refractory
USF piggyBac screen (Insert. mut.) USF PiggyBac Screen

Mutant phenotypes [+]

Species Stage Phenotype Reference Submitter
P. berghei ANKA Asexual
No difference
RMgm-909 Imported from RMgmDB
P. berghei ANKA Asexual
No difference
PlasmoGEM (Barseq) PlasmoGEM
P. berghei ANKA Gametocyte
No difference
RMgm-909 Imported from RMgmDB
P. berghei ANKA Ookinete
No difference
RMgm-909 Imported from RMgmDB
P. berghei ANKA Oocyst
No difference
RMgm-909 Imported from RMgmDB
P. berghei ANKA Sporozoite
No difference
RMgm-909 Imported from RMgmDB
P. berghei ANKA Liver
Difference from wild-type
RMgm-909
Numbers of nfu liver stage parasites in cultured hepatocytes were similar to those of WT parasites. Quantification of nfu- merosomes, merozoite-filled vesicles budding from mature liver stage parasites, showed a reduction 60% as compared to WT parasites.Prepatency was tested by either intravenous injection of 100 or 10,000 sporozoites or by exposure to bites of 57 infected Anopheles stephensi mosquitoes. Irrespective of the mode of sporozoite delivery, initiation of blood infection was comparable between nfu and WT-infected animals.
Imported from RMgmDB

More information

PlasmoDB PCHAS_0822600
GeneDB PCHAS_0822600
Malaria Metabolic Pathways Localisation images
Pathways mapped to
Previous ID(s) PC000001.04.0, PCAS_082210, PCHAS_082260
Orthologs PBANKA_0822300 , PF3D7_0921400 , PKNH_0719400 , PVP01_0719900 , PVX_099490 , PY17X_0825600
Google Scholar Search for all mentions of this gene