Disruptability [+]

Species Disruptability Reference Submitter
P. berghei ANKA
Possible
RMgm-675 Imported from RMgmDB
P. berghei ANKA
Possible
RMgm-672 Imported from RMgmDB
P. berghei ANKA
Possible
PlasmoGEM (Barseq) PlasmoGEM

Mutant phenotypes [+]

Species Stage Phenotype Reference Submitter
P. berghei ANKA Asexual
No difference
RMgm-675 Imported from RMgmDB
P. berghei ANKA Asexual
No difference
RMgm-672 Imported from RMgmDB
P. berghei ANKA Asexual
No difference
PlasmoGEM (Barseq) PlasmoGEM
P. berghei ANKA Gametocyte
No difference
RMgm-675 Imported from RMgmDB
P. berghei ANKA Gametocyte
No difference
RMgm-672 Imported from RMgmDB
P. berghei ANKA Ookinete
Difference from wild-type
RMgm-675
Normal numbers of ookinetes are produced. The speed of gliding of ookinetes obtained from in vitro cultures was moderately, albeit significantly, reduced.
Imported from RMgmDB
P. berghei ANKA Ookinete
Difference from wild-type
RMgm-672
Normal numbers of ookinetes are produced. The speed of gliding of ookinetes obtained from in vitro cultures was moderately, albeit significantly, reduced.
Imported from RMgmDB
P. berghei ANKA Oocyst
No difference
RMgm-675 Imported from RMgmDB
P. berghei ANKA Oocyst
No difference
RMgm-672 Imported from RMgmDB
P. berghei ANKA Sporozoite
Difference from wild-type
RMgm-675
Normal production of salivary gland sporozoites. Infectivity of mutant sporozoites to mice after intravenously injection is comparable to wild type sporozoites.Infectivity of mutant sporozoites to mice after mosquito feeding is strongly reduced.Mutant sporozoite show aberrant motility and substrate adhesion in vitro.Mutant sporozoites showed normal host cell traversal and invasion.
Imported from RMgmDB
P. berghei ANKA Sporozoite
Difference from wild-type
RMgm-672
Normal production of salivary gland sporozoites. Infectivity of mutant sporozoites to mice after intravenously injection is comparable to wild type sporozoites.Infectivity of mutant sporozoites to mice after mosquito feeding is strongly reduced.Mutant sporozoite show aberrant motility and substrate adhesion in vitro.Mutant sporozoites showed normal host cell traversal and invasion.
Imported from RMgmDB
P. berghei ANKA Liver
Difference from wild-type
RMgm-675
Infectivity of mutant sporozoites to mice after intravenously injection is comparable to wild type sporozoites.Infectivity of mutant sporozoites to mice after mosquito feeding is strongly reduced.Mutant sporozoites showed normal host cell traversal and invasion.
Imported from RMgmDB
P. berghei ANKA Liver
Difference from wild-type
RMgm-672
Infectivity of mutant sporozoites to mice after intravenously injection is comparable to wild type sporozoites.Infectivity of mutant sporozoites to mice after mosquito feeding is strongly reduced.Mutant sporozoites showed normal host cell traversal and invasion.
Imported from RMgmDB

More information

PlasmoDB PCHAS_0723400
GeneDB PCHAS_0723400
Malaria Metabolic Pathways Localisation images
Pathways mapped to
Previous ID(s) PC000514.02.0, PC000572.02.0, PC000782.03.0, PCHAS_072340
Orthologs PBANKA_0714300 , PF3D7_0816500 , PKNH_0503900 , PVP01_0518800 , PVX_089585 , PY17X_0714500
Google Scholar Search for all mentions of this gene