Disruptability [+]

Species Disruptability Reference Submitter
P. berghei ANKA
Possible
RMgm-4165 Imported from RMgmDB
P. falciparum 3D7
Possible
USF piggyBac screen (Insert. mut.) USF PiggyBac Screen

Mutant phenotypes [+]

Species Stage Phenotype Reference Submitter
P. berghei ANKA Asexual
No difference
RMgm-4165 Imported from RMgmDB
P. berghei ANKA Gametocyte
No difference
RMgm-4165 Imported from RMgmDB
P. berghei ANKA Ookinete
No difference
RMgm-4165 Imported from RMgmDB
P. berghei ANKA Oocyst
Difference from wild-type
RMgm-4165
Normal ookinete production/numbers. Oocyst numbers per mosquito were reduced below 50%. The number of oocyst-derived midgut sporozoites per oocyst remained unchanged; ookinete development and oocyst sporulation therefore do not require LIMP. limp sporozoites did not significantly accumulate in the haemolymph, but showed a 10-fold reduction in salivary gland invasion.
Imported from RMgmDB
P. berghei ANKA Sporozoite
Difference from wild-type
RMgm-4165
Normal ookinete production/numbers. Oocyst numbers per mosquito were reduced below 50%. The number of oocyst-derived midgut sporozoites per oocyst remained unchanged; ookinete development and oocyst sporulation therefore do not require LIMP. limp sporozoites did not significantly accumulate in the haemolymph, but showed a 10-fold reduction in salivary gland invasion.
Imported from RMgmDB
P. berghei ANKA Liver
Difference from wild-type
RMgm-4165
limp sporozoites did not significantly accumulate in the haemolymph, but showed a 10-fold reduction in salivary gland invasion. limp salivary gland sporozoites did not establish exoerythrocytic forms (EEFs) inside Huh7 hepatoma cells and were not infectious to mice.
Imported from RMgmDB

More information

PlasmoDB PCHAS_0607600
GeneDB PCHAS_0607600
Malaria Metabolic Pathways Localisation images
Pathways mapped to
Previous ID(s) PC403792.00.0, PCAS_060640, PCHAS_060760
Orthologs PBANKA_0605800 , PF3D7_1207300 , PKNH_1307200 , PVP01_1306400 , PVX_084400 , PY17X_0608300
Google Scholar Search for all mentions of this gene