Disruptability [+]

Species Disruptability Reference Submitter
P. berghei ANKA
Possible
PlasmoGEM (Barseq) PlasmoGEM
P. berghei ANKA
Possible
RMgm-5213 Imported from RMgmDB
P. falciparum 3D7
Possible
USF piggyBac screen (Insert. mut.) USF PiggyBac Screen
P. falciparum 3D7
Possible
RMgm-4998 Imported from RMgmDB

Mutant phenotypes [+]

Species Stage Phenotype Reference Submitter
P. berghei ANKA Asexual
No difference
PlasmoGEM (Barseq) PlasmoGEM
P. berghei ANKA Asexual
No difference
RMgm-5213 Imported from RMgmDB
P. berghei ANKA Gametocyte
No difference
RMgm-5213 Imported from RMgmDB
P. berghei ANKA Ookinete
Difference from wild-type
RMgm-5213
A strong reduction (>69%) in mature ookinete numbers.
Imported from RMgmDB
P. berghei ANKA Oocyst
Difference from wild-type
RMgm-5213
Reduced oocyst numbers (80% reduction).
Imported from RMgmDB
P. falciparum 3D7 Asexual
No difference
RMgm-4998 Imported from RMgmDB
P. falciparum 3D7 Gametocyte
No difference
RMgm-4998 Imported from RMgmDB
P. falciparum 3D7 Ookinete
No difference
RMgm-4998 Imported from RMgmDB
P. falciparum 3D7 Oocyst
Difference from wild-type
RMgm-4998
Ookinete motility comparable to wild type. Evidence is presented for ookinete defects in invasion and traversal of the midgut epithelium. Strongly reduced oocyst numbers.
Imported from RMgmDB
P. falciparum 3D7 Sporozoite
Difference from wild-type
RMgm-4998
Strongly reduced sporozoite numbers. No infection of mice by the bite of infected mosquitoes
Imported from RMgmDB
P. falciparum 3D7 Liver
Difference from wild-type
RMgm-4998
No infection of mice by the bite of infected mosquitoes
Imported from RMgmDB

More information

PlasmoDB PBANKA_1457700
GeneDB PBANKA_1457700
Malaria Metabolic Pathways Localisation images
Pathways mapped to
Previous ID(s) PB000587.02.0, PB000589.02.0, PBANKA_145770
Orthologs PCHAS_1460000 , PF3D7_1244500 , PKNH_1463700 , PVP01_1461600 , PVX_101120 , PY17X_1460300
Google Scholar Search for all mentions of this gene