Disruptability [+]

Species Disruptability Reference Submitter
P. berghei ANKA
Possible
RMgm-839 Imported from RMgmDB
P. falciparum 3D7
Possible
24602217 Theo Sanderson, Wellcome Trust Sanger Institute

Mutant phenotypes [+]

Species Stage Phenotype Reference Submitter
P. berghei ANKA Asexual
No difference
RMgm-839 Imported from RMgmDB
P. berghei ANKA Gametocyte
Difference from wild-type
RMgm-839
Normal production of gametocytes. The production of male gametes is affected. The male gametocyte displays abnormal exflagellation; instead of forming 8 gametes, it produced only one, shared thicker flagellum. Evidence is presented that rupture of the erythrocyte membrane is blocked and thereby preventing egress of male gametes from the erythrocyte.
Imported from RMgmDB
P. berghei ANKA Ookinete
Difference from wild-type
RMgm-839
Strongly reduced ookinete production as a result of aberrant production of male gametes. The male gametocyte displays abnormal exflagellation; instead of forming 8 gametes, it produced only one, shared thicker flagellum. Evidence is presented that rupture of the erythrocyte membrane is blocked and thereby preventing egress of male gametes from the erythrocyte. Evidence is presented that female gametocytes/female gametes show normal egress from the erythrocyte.
Imported from RMgmDB
P. berghei ANKA Oocyst
Difference from wild-type
RMgm-839
Strongly reduced oocyst production as a result of strongly reduced ookinete production.
Imported from RMgmDB
P. falciparum 3D7 Asexual
No difference
24602217 Theo Sanderson, Wellcome Trust Sanger Institute

More information

PlasmoDB PBANKA_1432400
GeneDB PBANKA_1432400
Malaria Metabolic Pathways Localisation images
Pathways mapped to
Previous ID(s) PB000619.01.0, PB001069.01.0, PBANKA_143240
Orthologs PCHAS_1434400 , PF3D7_1216700 , PKNH_1436300 , PVP01_1435500 , PVX_123515 , PY17X_1434700
Google Scholar Search for all mentions of this gene