Disruptability [+]

Species Disruptability Reference Submitter
P. berghei ANKA
Possible
RMgm-4105 Imported from RMgmDB
P. berghei ANKA
Possible
PlasmoGEM (Barseq) PlasmoGEM
P. falciparum 3D7
Possible
USF piggyBac screen (Insert. mut.) USF PiggyBac Screen
P. yoelii yoelii 17X
Possible
RMgm-4389 Imported from RMgmDB

Mutant phenotypes [+]

Species Stage Phenotype Reference Submitter
P. berghei ANKA Asexual
No difference
RMgm-4105 Imported from RMgmDB
P. berghei ANKA Gametocyte
No difference
RMgm-4105 Imported from RMgmDB
P. berghei ANKA Ookinete
Difference from wild-type
RMgm-4105
Normal gametocyte production and gamete formation. Evidence for normal fertilisation. Formation of retort shaped, immature ookinetes. Strongly reduced mature ookinete production.
Imported from RMgmDB
P. berghei ANKA Oocyst
Difference from wild-type
RMgm-4105
Strongly reduced mature ookinete production. Strongly reduced oocyst production. Oocysts produced were very small without sporulating. No sporozoites formed.
Imported from RMgmDB
P. berghei ANKA Sporozoite
Difference from wild-type
RMgm-4105
Strongly reduced mature ookinete production. Strongly reduced oocyst production. Oocysts produced were very small without sporulating. No sporozoites formed.
Imported from RMgmDB
P. yoelii yoelii 17X Asexual
No difference
RMgm-4389 Imported from RMgmDB
P. yoelii yoelii 17X Gametocyte
No difference
RMgm-4389 Imported from RMgmDB
P. yoelii yoelii 17X Ookinete
No difference
RMgm-4389 Imported from RMgmDB
P. yoelii yoelii 17X Oocyst
Difference from wild-type
RMgm-4389
Strongly reduced oocyst and sporozoite production. Low numbers of sporozoites are infective to mice. Evidence is presented that early oocyst development (day1-3) is normal.
Imported from RMgmDB
P. yoelii yoelii 17X Sporozoite
Difference from wild-type
RMgm-4389
Strongly reduced oocyst and sporozoite production. Low numbers of sporozoites are infective to mice. Evidence is presented that early oocyst development (day1-3) is normal.
Imported from RMgmDB

More information

PlasmoDB PBANKA_1231600
GeneDB PBANKA_1231600
Malaria Metabolic Pathways Localisation images
Pathways mapped to
Previous ID(s) ApiAP2, PB000976.01.0, PB300179.00.0, PB300549.00.0, PB300984.00.0, PB402027.00.0, PBANKA_123160
Orthologs PCHAS_1232200 , PF3D7_0516800 , PKNH_1016500 , PVP01_1017200 , PVX_080410 , PY17X_1235000
Google Scholar Search for all mentions of this gene