Disruptability [+]

Species Disruptability Reference Submitter
P. berghei ANKA
Possible
PlasmoGEM (Barseq) PlasmoGEM
P. falciparum 3D7
Refractory
USF piggyBac screen (Insert. mut.) USF PiggyBac Screen

Mutant phenotypes [+]

Species Stage Phenotype Reference Submitter
P. berghei ANKA Asexual
Attenuated
PlasmoGEM (Barseq) PlasmoGEM

Imaging data (from Malaria Metabolic Pathways)

Immunoelectron microscopy showing the localization of PfRhop148 in the rhoptries within the developing merozoites in the schizont. Parasites were fixed with 1% paraformaldehyde and 0.1% glutaraldehyde. Staining was detected with rabbit anti-Rhop148 and anti-rabbit gold (10 nm). Bar represents 250 nm. IFA analysis showing stage-specific localization of PfRhop148. MAb 3C2 raised against the recombinant protein was used against staged synchronized parasites. Lower panels represent the merged image with DAPI dye.Lobo CA, Rodriguez M, Hou G, Perkins M, Oskov Y, Lustigman S. Characterization of PfRhop148, a novel rhoptry protein of Plasmodium falciparum. Mol Biochem Parasitol. 2003 128:59-65. Copyright Elsevier 2009.

See original on MMP

More information

PlasmoDB PBANKA_1142300
GeneDB PBANKA_1142300
Malaria Metabolic Pathways Localisation images
Pathways mapped to
Previous ID(s) PB000699.01.0, PB000869.00.0, PBANKA_114230
Orthologs PCHAS_1141800 , PF3D7_1366400 , PKNH_1104900 , PVP01_1105600 , PVX_115280 , PY17X_1143600
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