Disruptability [+]

Species Disruptability Reference Submitter
P. berghei ANKA
Possible
PlasmoGEM (Barseq) Imported from PlasmoGEM
P. berghei ANKA
Possible
RMgm-4412 Imported from RMgmDB

Mutant phenotypes [+]

Species Stage Phenotype Reference Submitter
P. berghei ANKA Asexual
No difference
RMgm-4412 Imported from RMgmDB
P. berghei ANKA Gametocyte
No difference
RMgm-4412 Imported from RMgmDB
P. berghei ANKA Ookinete
No difference
RMgm-4412 Imported from RMgmDB
P. berghei ANKA Oocyst
No difference
RMgm-4412 Imported from RMgmDB
P. berghei ANKA Sporozoite
Difference from wild-type
RMgm-4412
Not different from wild type
Imported from RMgmDB
P. berghei ANKA Liver
No difference
RMgm-4412 Imported from RMgmDB

Imaging data (from Malaria Metabolic Pathways)

Stage-specific localization of PfCS using confocal microscopy. The rows in each column represent four parasitic stages. First row (from the top), ring stage; second row, trophozoite; third row, schizont; fourth row, segmenter. The scale bars represent 1 mm. Left column (green), DNA stain with Hoechst dye; centre column (red), PfCS immunofluorescence with AbPfCS1; right column, composite. The appearance of a dispersed immunofluorescence pattern surrounding the nuclear stain and the absence of a discrete crescent-shaped signal clearly indicate that PfCS is cytosolic and not located to the apicoplast.Fitzpatrick T, Ricken S, Lanzer M, Amrhein N, Macheroux P, Kappes B. Subcellular localization and characterization of chorismate synthase in the apicomplexan Plasmodium falciparum. Mol Microbiol. 2001 40:65-75.

See original on MMP

More information

PlasmoDB PBANKA_1121900
GeneDB PBANKA_1121900
Malaria Metabolic Pathways Localisation images
Pathways mapped to
Previous ID(s) PB000663.00.0, PBANKA_112190
Orthologs PCHAS_1121400 , PF3D7_0623000 , PKNH_1127200 , PVP01_1126500 , PVX_114265 , PY17X_1123300
Google Scholar Search for all mentions of this gene