Disruptability [+]

Species Disruptability Reference Submitter
P. berghei ANKA
Possible
PlasmoGEM (Barseq) PlasmoGEM
P. falciparum 3D7
Refractory
USF piggyBac screen (Insert. mut.) USF PiggyBac Screen

Mutant phenotypes [+]

Species Stage Phenotype Reference Submitter
P. berghei ANKA Asexual
No difference
PlasmoGEM (Barseq) PlasmoGEM
P. falciparum 3D7 Asexual
Egress defect
34973333 (Knock down)
\"By regulating the expression of HAD5 in transgenic parasites with a TetR-DOZI-inducible knockdown system, we demonstrated that HAD5 is required for malaria parasite egress and erythrocyte reinvasion, and we assessed the role of HAD5 in GPI anchor synthesis by autoradiography of radiolabeled glucosamine and thin layer chromatography.\"
Theo Sanderson, Francis Crick Institute

More information

PlasmoDB PBANKA_0501700
GeneDB PBANKA_0501700
Malaria Metabolic Pathways Localisation images
Pathways mapped to
Previous ID(s) PB001216.00.0, PB300192.00.0, PBANKA_050170
Orthologs PCHAS_0501800 , PF3D7_1017400 , PKNH_0601600 , PVP01_0602600 , PVX_001740 , PY17X_0502700
Google Scholar Search for all mentions of this gene