Disruptability [+]

Species Disruptability Reference Submitter
P. berghei ANKA
Possible
PlasmoGEM (Barseq) PlasmoGEM
P. falciparum 3D7
Refractory
USF piggyBac screen (Insert. mut.) USF PiggyBac Screen

Mutant phenotypes [+]

Species Stage Phenotype Reference Submitter
P. berghei ANKA Asexual
No difference
PlasmoGEM (Barseq) PlasmoGEM

Imaging data (from Malaria Metabolic Pathways)

Ubiquitylation proteins localize to the apicoplast in Plasmodium falciparum. Immunofluorescence assays detecting the respective ubiquitylation factorindicated (white lettering) in the left-most panel. Proteins were detected by tagging with an HA or GFP epitope in the genomic locus (C, D), by ectopic fusion with partial coding sequence (E), or by using an antibody raised again recombinant protein (C). Staining for the apicoplast markers Cpn60 and ACP is shown in the second lane. Merged images also show DAPI staining for P. falciparumAgrawal S, Chung DW, Ponts N, van Dooren GG, Prudhomme J, Brooks CF, Rodrigues EM, Tan JC, Ferdig MT, Striepen B, Le Roch KG. An Apicoplast Localized Ubiquitylation System Is Required for the Import of Nuclear-encoded Plastid Proteins. PLoS Pathog. 2013 9(6):e1003426

See original on MMP

More information

PlasmoDB PBANKA_0410100
GeneDB PBANKA_0410100
Malaria Metabolic Pathways Localisation images
Pathways mapped to
Previous ID(s) PB000247.01.0, PB107572.00.0, PBANKA_041010
Orthologs PCHAS_0411000 , PF3D7_0312100 , PKNH_0830300 , PVP01_0828100 , PVX_119710 , PY17X_0412600
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